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Ramezani et al., 2016

* Significant difference with the Sham group (p 0.05) # Significant difference with the thioacetamide group (p0.05) Also, the injection of 200 mg/kg green tea extract has a more appropriate effect on decreasing liver enzymes level compared with the injection of glutathione

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Interestingly, SIRT1 promotes mitophagy by deacetylating FOXO3a, which upregulates Rab7 expression, a small GTP-binding protein that facilitates autophagosome-lysosome fusion, thereby increasing mitophagy flux (Wan et al

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